Hydrogen

No known toxicity for H₂ [7].

Experiments on mice show that hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response. This is most likely done through the TLR4-NF-κB pathway [7].

A study with rats suggests that H₂ is a potential alternative therapy to prevent or minimize rhabdomyolysis induced acute kidney injury, possibly via hydrogen gas’ antioxidant, anti-inflammatory, anti-apoptotic and anti-necroptotic properties [8].