Lithium has been used as the first mood stabilizer and is still the first line treatment option. It is commonly prescribed for a manic episode in bipolar disorder as well as maintenance therapy of bipolar disorder in a patient with a history of a manic episode. The primary target symptoms of lithium are mania and unstable mood .
Lithium is prescribed for major depressive disorder as adjunct therapy, bipolar disorder without a history of mania, treatment of vascular headaches, and neutropenia .
Lithium is used for Li-ion batteries with high energy and power density in combination with cobalt, nickel, manganese and a number of other metals .